Running a successful medical practice requires much more than excellent patient care—it also demands efficient scheduling, billing, electronic health record (EHR) management, telehealth integration, and compliance. DrChrono is widely recognized for offering a strong EHR and practice management system. However, it’s not the perfect solution for every healthcare provider.

Some practices find DrChrono lacking in advanced customization, others want more affordable pricing, while some require specialty-specific templates. That’s where DrChrono alternatives step in. The right medical practice management software can help streamline workflows, boost patient engagement, and improve revenue cycle management.

In this article, we’ll explore the best DrChrono competitors in 2025, highlighting their features, benefits, and suitability for different practice sizes. Whether you’re searching for an all-in-one cloud EHR with billing, an ONC-certified practice management system for small practices, or an enterprise-grade interoperable EHR for hospitals, this guide will help you find the perfect fit.

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1. athenaOne (Athenahealth)

Why It’s a Top DrChrono Alternative:
Athenahealth consistently ranks among the top EHR and practice management providers. It’s a cloud-based all-in-one medical software offering electronic prescribing, revenue cycle management, telehealth, and advanced patient engagement tools.

Key Features:

• AI-driven analytics and reporting
  
• Built-in e-prescribing and compliance tracking
  
• Patient portal with secure messaging
  
• Strong billing and claims management
  

Best For: Medium to large practices needing cloud-based EHR software with revenue cycle management and advanced interoperability.

Long-Tail Keywords to Note:
“all-in-one EHR with billing and telehealth,” “best medical practice management software with patient engagement tools.”

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2. RXNT

Why It’s a Great Fit:
RXNT is a cloud-based, ONC-certified EHR and practice management platform designed for smaller practices looking for affordability without compromising compliance.

Key Features:

• Free implementation and training
  
• Integrated practice management, billing, and EHR
  
• Mobile access for clinicians
  
• Built-in reporting tools
  

Best For: Small practices and startups searching for ONC-certified EHR with free setup and training.

Semantic Keywords:
“affordable EHR software for small practices,” “HIPAA-compliant cloud practice management system.”

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3. AdvancedMD

Why Practices Love It:
AdvancedMD offers a customizable medical practice management system designed for scalability. With strong EHR capabilities, integrated telemedicine, and billing features, it’s ideal for mid-sized to large practices.

Key Features:

• Mobile-friendly cloud EHR
  
• Custom workflows and specialty templates
  
• Telemedicine integration
  
• Revenue cycle optimization tools
  

Best For: Providers seeking scalable cloud practice management software with customizable templates.

Keywords to Include:
“telehealth-enabled medical practice management software,” “customizable EHR templates for specialty practices.”

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4. Tebra (formerly Kareo + PatientPop)

Why It’s Popular:
Tebra merges the strengths of Kareo’s practice management with PatientPop’s patient engagement. It provides easy-to-use practice management software with billing and telehealth, perfect for small clinics.

Key Features:

• Simple onboarding and setup
  
• Billing and scheduling integration
  
• Telehealth features built-in
  
• Patient engagement dashboards
  

Best For: Small practices looking for user-friendly EHR and telehealth solutions.

SEO Keywords:
“best practice management software for small practices,” “telehealth and billing EHR with patient engagement.”

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5. eClinicalWorks (eCW)

Why It Stands Out:
eClinicalWorks is known for its robust patient engagement software and telehealth integration, along with a flexible pricing model that suits both small and mid-size practices.

Key Features:

• Population health management
  
• Telehealth and mobile app for patients
  
• Integrated billing and claims submission
  
• Secure messaging and engagement
  

Best For: Clinics needing affordable telehealth-enabled EHR with patient tracking.

Keywords to Use:
“EHR with patient engagement and telehealth,” “practice management system for small to mid-size practices.”

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6. NextGen Healthcare

Why Providers Choose It:
NextGen focuses on specialty-specific EHR templates and robust reporting tools, making it perfect for specialty care and large practices.

Key Features:

• Specialty workflows for orthopedics, dermatology, etc.
  
• Revenue cycle management (RCM) tools
  
• Interoperability and compliance support
  
• Mobile patient portal
  

Best For: Specialty providers searching for specialty-specific EHR with RCM.

SEO Keywords:
“specialty EHR software with revenue cycle management,” “compliance-focused practice management system.”

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7. Epic

Why It’s a Leader:
Epic dominates in hospital systems and large health networks. Known for its enterprise-level EHR, it provides unmatched scalability and interoperability.

Key Features:

• Advanced patient portal (MyChart)
  
• Interoperable modules across health systems
  
• Customizable workflows
  
• Data-driven clinical insights
  

Best For: Large hospitals and enterprise-scale providers needing enterprise-grade interoperable EHR.

Keywords:
“hospital EHR system with enterprise scalability,” “interoperable EHR software for large health systems.”

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8. CareCloud

Why Practices Like It:
CareCloud offers a modern, intuitive cloud-based EHR and practice management solution designed for growing practices.

Key Features:

• Clean and modern interface
  
• Customizable dashboards and reporting
  
• Telehealth integration
  
• Revenue cycle automation
  

Best For: Clinics looking for modern EHR with intuitive dashboards and telehealth.

Keywords:
“cloud-based medical practice management software,” “scalable EHR with modern interface.”

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9. OpenEMR

Why It’s Unique:
OpenEMR is a free, open-source, ONC-certified EHR system used worldwide. It’s ideal for practices wanting complete control without licensing costs.

Key Features:

• Multilingual support
  
• Scheduling, billing, and patient portal
  
• Strong compliance features
  
• Large community support
  

Best For: Budget-conscious practices seeking open-source healthcare software.

Keywords:
“free ONC-certified EHR software,” “open-source medical practice management system with billing.”

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10. Praxis EMR

Why It’s Innovative:
Praxis EMR uses AI to adapt to each provider’s workflow, offering a template-free EHR system that gets smarter with use.

Key Features:

• AI-driven charting and learning
  
• Custom workflows without rigid templates
  
• Advanced reporting
  
• Affordable pricing for small practices
  

Best For: Providers looking for AI-powered EHR with template-free workflows.

Keywords:
“AI-based EMR software for small practices,” “template-free EHR with adaptive learning.”

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Final Thoughts

Choosing the best DrChrono alternative depends on your practice’s size, specialty, and long-term goals. Smaller practices may benefit from RXNT, Tebra, or CareCloud for affordability and ease of use, while larger hospitals might prefer Epic or NextGen Healthcare for scalability. Practices requiring flexibility may find Praxis EMR or OpenEMR appealing, while those focused on growth and analytics can benefit from athenaOne or AdvancedMD.At AlternativeKnot, we believe that every practice deserves software that reduces administrative burdens, empowers clinicians, and improves patient care. By considering these DrChrono alternatives for medical practice management software, you can knot together a smarter, future-ready solution tailored to your healthcare needs.